Ufit-Exercise is a hardware-software integrated system that creates an instructive, interactive, and immersive environment for Physiotherapy Scoliosis Specific Exercises (PSSEs). By using patient digital twin (PDT), a digital or virtual copy of an individual patient, the diagnosis of scoliosis and the assessment of spine deformity can be performed in 3D space thus improving the completeness of assessment and the design of PSSEs. By representing the prescribed PSSEs in 3D games via animating the PDT